Vasopresina

Presentación

Solución 20 unidades/mL — documentado: Fresenius Kabi y American Regent (FDA)

¿Para qué sirve vasopresina? Indicaciones autorizadas

1 INDICATIONS AND USAGE Vasopressin injection is indicated to increase blood pressure in adults with vasodilatory shock who remain hypotensive despite fluids and catecholamines. • Vasopressin injection is indicated to increase blood pressure in adults with vasodilatory shock who remain hypotensive despite fluids and catecholamines. ( 1 )

FDA (DailyMed) · VASOPRESSIN · Indications and usage · texto original en inglés

1 INDICATIONS AND USAGE Vasopressin injection is indicated to increase blood pressure in adults with vasodilatory shock who remain hypotensive despite fluids and catecholamines. Vasopressin injection is indicated to increase blood pressure in adults with vasodilatory shock who remain hypotensive despite fluids and catecholamines. ( 1 )

FDA (DailyMed) · Vasopressin · Indications and usage · texto original en inglés

Contraindicaciones de vasopresina

4 CONTRAINDICATIONS Vasopressin injection 1 mL single dose vial does not contain chlorobutanol and is therefore contraindicated only in patients with a known allergy or hypersensitivity to 8-L-arginine vasopressin. • Vasopressin injection 1 mL single dose vial does not contain chlorobutanol and is therefore contraindicated only in patients with a known allergy or hypersensitivity to 8-L-arginine vasopressin. ( 4 )

FDA (DailyMed) · VASOPRESSIN · Contraindications · texto original en inglés

4 CONTRAINDICATIONS Vasopressin injection 1 mL single-dose vial and 10 mL multiple-dose vial are contraindicated in patients with known allergy or hypersensitivity to 8-L-arginine vasopressin or chlorobutanol. Vasopressin injection 1 mL single-dose vial and 10 mL multiple-dose vial are contraindicated in patients with known allergy or hypersensitivity to 8-L-arginine vasopressin or chlorobutanol. ( 4 )

FDA (DailyMed) · Vasopressin · Contraindications · texto original en inglés

Ajuste en insuficiencia renal

In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy [see Warnings and Precautions ( 5 ), Adverse Reactions ( 6 ), and Clinical Pharmacology ( 12.3 )] .

FDA (DailyMed) · VASOPRESSIN · Use in specific populations · texto original en inglés

In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy [see Warnings and Precautions ( 5.1 , 5.2 ), Adverse Reactions ( 6 ), and Clinical Pharmacology ( 12.3 )] .

FDA (DailyMed) · Vasopressin · Use in specific populations · texto original en inglés

Ajuste en insuficiencia hepática

In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy [see Warnings and Precautions ( 5 ), Adverse Reactions ( 6 ), and Clinical Pharmacology ( 12.3 )] .

FDA (DailyMed) · VASOPRESSIN · Use in specific populations · texto original en inglés

In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy [see Warnings and Precautions ( 5.1 , 5.2 ), Adverse Reactions ( 6 ), and Clinical Pharmacology ( 12.3 )] .

FDA (DailyMed) · Vasopressin · Use in specific populations · texto original en inglés

Reconstitución de vasopresina

No requiere.

Dilución de vasopresina

SF 0.9% o glucosa 5% a 0.1 o 1 unidad/mL.

Administración de vasopresina

Infusión IV continua con bomba.

Estabilidad y periodo de validez

Compatibilidad de vasopresina

Compatible con

• SF 0.9%
• Glucosa 5%

Conservación y protección de la luz

Sin abrir: refrigerar 2–8 °C. Puede pasar a temperatura ambiente (≤25 °C) por un tiempo que DEPENDE DEL FABRICANTE Y DEL VIAL; no volver a refrigerar.

Ninguna de las fuentes indica protección de la luz.

Advertencias

• MEDICAMENTO DE ALTO RIESGO (vasopresor).
• Dosis en unidades/min, distintas entre choque séptico y poscardiotomía.

Diferencias entre fuentes oficiales

• El tiempo a temperatura ambiente depende del vial: 12 meses (1 mL) vs 2 meses (10 mL, American Regent).

Fuentes

1. FDA (DailyMed) · Vasopressin InjectionFresenius Kabi USA, LLC · Vial 20 unidades/mL (1 mL) · versión 2025-02-15
2. FDA (DailyMed) · VasopressinAmerican Regent, Inc. · Viales 20 unidades/mL de 1 y 10 mL · versión 2024-10-31

Interacciones de vasopresina

8 medicamentos del catálogo con una interacción documentada en sus fichas oficiales. Abre cada una para ver el efecto, la recomendación y su fuente.

• ClorpromazinaModerada
• EnalaprilModerada
• FoscarnetModerada
• HaloperidolModerada
• KetaminaModerada
• LevomepromazinaModerada
• Norepinefrina (noradrenalina)Moderada
• VincristinaModerada

Diagnósticos relacionados

Diagnósticos que la ficha técnica de vasopresina menciona en sus indicaciones. Cada uno abre su definición y los demás medicamentos indicados.

• Choque (shock)

Identificación

RxNorm

11149