Nicardipino

Presentación

Solución 2.5 mg/mL — documentado: Hikma (FDA)

¿Para qué sirve nicardipino? Indicaciones autorizadas

1 INDICATIONS AND USAGE Nicardipine hydrochloride injection, USP is a calcium channel blocker indicated for the short-term treatment of hypertension when oral therapy is not feasible. 1.1 Hypertension Nicardipine hydrochloride injection, USP is indicated for the short-term treatment of hypertension when oral therapy is not feasible or desirable. For prolonged control of blood pressure, transfer patients to oral medication as soon as their clinical condition permits [see Dosage and Administration (2.6) ].

FDA (DailyMed) · Nicardipine Hydrochloride · Indications and usage · texto original en inglés

Dosis máximas y límites de nicardipino

Límites que la fuente establece para un contexto concreto. Una dosis recomendada no equivale a una dosis máxima; la posología completa por indicación, edad y peso está en la app.

Contraindicaciones de nicardipino

4 CONTRAINDICATIONS Do not use in patients with advanced aortic stenosis ( 4.1 ). 4.1 Advanced Aortic Stenosis Do not use nicardipine in patients with advanced aortic stenosis because of the afterload reduction effect of nicardipine. Reduction of diastolic pressure in these patients may worsen rather than improve myocardial oxygen balance.

FDA (DailyMed) · Nicardipine Hydrochloride · Contraindications · texto original en inglés

Ajuste en insuficiencia renal

Impaired Cardiac, Hepatic, or Renal Function: Monitor closely when titrating nicardipine hydrochloride injection in patients with congestive heart failure or impaired hepatic or renal function [see Warnings and Precautions (5.4 , 5.5 and 5.6) ]. 2.6 Transfer to Oral Antihypertensive Agents If treatment includes transfer to an oral antihypertensive agent other than nicardipine capsules, initiate oral therapy upon discontinuation of nicardipine hydrochloride injection.

FDA (DailyMed) · Nicardipine Hydrochloride · Dosage and administration · texto original en inglés

In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal or cardiac function, and concomitant disease of other drug therapy.

FDA (DailyMed) · Nicardipine Hydrochloride · Use in specific populations · texto original en inglés

Ajuste en insuficiencia hepática

Impaired Cardiac, Hepatic, or Renal Function: Monitor closely when titrating nicardipine hydrochloride injection in patients with congestive heart failure or impaired hepatic or renal function [see Warnings and Precautions (5.4 , 5.5 and 5.6) ]. 2.6 Transfer to Oral Antihypertensive Agents If treatment includes transfer to an oral antihypertensive agent other than nicardipine capsules, initiate oral therapy upon discontinuation of nicardipine hydrochloride injection.

FDA (DailyMed) · Nicardipine Hydrochloride · Dosage and administration · texto original en inglés

In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal or cardiac function, and concomitant disease of other drug therapy.

FDA (DailyMed) · Nicardipine Hydrochloride · Use in specific populations · texto original en inglés

Reconstitución de nicardipino

No requiere.

Dilución de nicardipino

Vial: diluir a 0.1 mg/mL (25 mg en 240 mL) en SF 0.9% o glucosa 5%.

Administración de nicardipino

Infusión IV continua con bomba. En vena periférica, cambiar el sitio cada 12 h (flebitis).

Estabilidad y periodo de validez

Compatibilidad de nicardipino

Compatible con

• SF 0.9%
• Glucosa 5%

Incompatible con

• Bicarbonato de sodio
• Ringer lactato

Conservación y protección de la luz

A 20–25 °C; evitar temperaturas elevadas.

Proteger de la luz hasta su uso.

Advertencias

• No usar si hay precipitado o cristales.

Fuentes

1. FDA (DailyMed) · Nicardipine HydrochlorideHikma Pharmaceuticals USA Inc. · Vial 25 mg/10 mL (2.5 mg/mL) · versión 2024-08-24

Interacciones de nicardipino

4 medicamentos del catálogo con una interacción documentada en sus fichas oficiales. Abre cada una para ver el efecto, la recomendación y su fuente.

• Bicarbonato de sodioMayor
• TacrolimusMayor
• FenitoínaModerada
• PosaconazolModerada

Identificación

SNOMED CT (VTM)

108526002

RxNorm

7396